Cees Dekker’s group recently published progress toward nanopore protein sequencing. The work addresses one of the fundamental issues in nanopore protein sequencing, controlling the translocation speed.
Without this, peptides translocate too quickly for individual amino acids to be detected (for more context on this see the Dreampore post). As there are no established techniques for controlling peptide translocation the Dekker approach links a peptide to a DNA molecule. This allows motion control techniques established for DNA sequencing to be applied to protein sequencing.
Empowered by the Helmet of Fate, Doctor Fate is a Lord of Order who has been fighting the forces of Chaos with magic since 1940. In the comics, the Helmet of Fate has taken a turn for the worst in the Lazarus Planet comic book event. Batman wears the helmet as he fights a devil and the helmet is destroyed and left on Lazarus Island. Working for Amanda Waller, Peacemaker infiltrates the island and locates the broken pieces which then form into the Helmet of Hate.
King Charles was due to attend the Easter Matins service today, where he plans to sit slightly apart from others at St George’s Chapel in Windsor, for the sake of his health. The King is still taking his recovery steadily, although he has been increasingly resuming duties. This will be his first official public appearance, since his diagnosis.
A palace source told The Telegraph it’s a “sign of things heading in the right direction”.
Last week, we bid farewell to Charlie Munger, the legendary Vice Chairman of Berkshire Hathaway whose wisdom profoundly influenced millions of people, including me. Munger was often described as Warren Buffett’s right-hand man; in reality, he was Buffett’s equal partner for over 50 years at the firm and attained a net worth of $2.7 billion through long-term investing.
Munger was also a voracious learner and one of the world’s best thinkers on human behavior.
Stop if you read this here before (actually, don’t stop, keep reading): Beer is friggin’ weird right now. Just a few years ago, every brewery was poised for growth as the market was growing by double digits. Now, people aren’t drinking as much beer. (Aside: You should follow my buddy, Bryan Roth, on Twitter and his ongoing “nobody likes beer anymore” thread.)
For Mark Neumann, founder and owner of Chemung County’s Upstate Brewing, it isn’t “nobody likes beer anymore,” it’s “let me sell all my beer in-house, so I can control the market, prices, and margins.