Conjugated equine estrogens (CEE), also known as Premarin, named because it comes from pregnant mares urine, was the industry standard for menopause hormone therapy for years until all estrogens took a hit with the Women’s Health Initiative (WHI). Once the dust settled, the recommended first-line therapy for symptoms of menopause became transdermal estradiol due to the lower risk of blood clots. However, there has been a renewed interest in Premarin due to the fact that it is associated with a lower long-term risk of breast cancer (when used without a progestin), and it is available in combination with bazedoxifene as another option for menopause hormone therapy without progesterone or a progestin (read more about that option here).

Watch video on TwitterView most updated version of this post on SubstackSearch our full archivesShare Preston Glass is an award-winning songwriter, musician, and producer. He and his brother Alan Glass got their start in the music business during the early 1980s working as staff songwriters for Thom Bell and Narada Michael Walden. Born on Fort Ord military base near Monterey, California, and raised in New Orleans, Glass’ mother and grandfather were both music teachers.

For Cunk On Earth, we wanted to do a version of the gag we liked doing where Philomena’s grand historical story would keeping getting stuck on a repeated overlong clip of the opening titles of Brush Strokes, the show knocked off course like a dog returning to a weird smell. This had been so much fun to drop into Cunk On Britain – the wait-for-it, the idea that the first episode of Brush Strokes going out was, in historical terms, a fixed point of measurement, the same as the moon landing or the birth of Christ.

I have on a few occasions had a chicken on my head. When the ladies were a bit younger and liked to perch on my shoulder, they often made the trek up my hair and on top of my head. (Though I always worried over it they never had an accident while up there.) It’s hard not to feel festive with a chicken “hat” consisting of exactly one live chicken. But now that the girls are bigger and have better things to do than sit on me for more than a few seconds at a time, my head is sadly unadorned.

When it comes to cult followings and sheer gnarliness of food, there is one ramen chain that conquers them all: Ramen Jiro.  Jiro's unique, over-the-top bowls have made it one of Japan's most divisive food phenomenons. In short, Jiro's ramen is everything that Japanese cuisine is famously NOT. It's ridiculously heavy and fatty. It uses cheap, easily-sourced ingredients. The bowls are thrown together hastily, rather than assembled with care. Portion sizes are enormous, and the ramen shops themselves tend to be grimy and dirty.